he Effect of Spinal and General Anesthesia on Inflammatory Response Measured by Delta Neutrophil Index in Patients Undergoing Total Knee Arthroplasty: A Prospective Observational Study
Status: Completed
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
This study aims to compare the effects of spinal versus general anesthesia on the inflammatory response measured by Delta Neutrophil Index (DNI) in patients undergoing total knee arthroplasty. The study is prospective and observational. A total of at least 84 patients will be included, with anesthesia type determined according to routine clinical practice. Preoperative and postoperative blood tests will be analyzed, and no additional blood samples will be required.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:
• Patients scheduled for total knee arthroplasty
• Age ≥ 18 years
• ASA physical status classification I-III
Locations
Other Locations
Turkey
University of Health Sciences, Elazığ Fethi Sekin City Hospital
Elâzığ
Time Frame
Start Date: 2025-09-22
Completion Date: 2025-10-22
Participants
Target number of participants: 84
Treatments
Spinal Anesthesia Group
Patients undergoing total knee arthroplasty under spinal anesthesia. The choice of anesthesia is based on clinical decision-making in routine practice.
General Anesthesia Group
Patients undergoing total knee arthroplasty under general anesthesia. The choice of anesthesia is based on clinical decision-making in routine practice.
Related Therapeutic Areas
Sponsors
Leads: Elazıg Fethi Sekin Sehir Hastanesi